Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564280 | 0.91 | HCRTR1 (0.37) | MAPTGAAHSD17B10ALDH1A1HTT | |
| SCHEMBL22564215 | 0.90 | MAPT (0.41) | MAPTTSHRHTTNPSR1KDM4E | |
| SCHEMBL22564211 | 0.90 | ALDH1A1 (0.36) | MAPTGAATSHRMAPK1HSD17B10 | |
| SCHEMBL22563853 | 0.89 | HTT (0.39) | HSD17B10VDRALDH1A1HTTNPSR1 | |
| SCHEMBL22564049 | 0.89 | SMN1; SMN2 (0.36) | MAPTALDH1A1HTTNPSR1KDM4E | |
| SCHEMBL22564309 | 0.89 | NPC1 (0.37) | SMN1; SMN2LMNANPC1RAB9ACTSD | |
| SCHEMBL22564542 | 0.89 | NPC1 (0.37) | MAPTGAAHTTSMN1; SMN2LMNA | |
| SCHEMBL22564338 | 0.88 | CTSD (0.35) | MAPTHTTNPSR1SMN1; SMN2LMNA | |
| SCHEMBL22564534 | 0.88 | LMNA (0.39) | MAPTHTTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL22564307 | 0.88 | NPC1 (0.36) | MAPTHTTSMN1; SMN2LMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |