Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | JAK3 | P52333 | 3/20 | 0.38 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564396 | 0.90 | KDM4E (0.37) | LMNAHTTSMN1; SMN2PARP1MAPT | |
| SCHEMBL22563853 | 0.89 | HTT (0.39) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22563971 | 0.88 | MAPT (0.40) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22564338 | 0.88 | CTSD (0.35) | LMNAHTTSMN1; SMN2JAK2NPC1 | |
| SCHEMBL22564307 | 0.88 | NPC1 (0.36) | LMNAHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL22564143 | 0.88 | IRAK4 (0.47) | HTTSMN1; SMN2JAK3PARP1JAK1 | |
| SCHEMBL22564299 | 0.87 | KMT2A (0.34) | LMNAHTTSMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL18504554 | 0.87 | LMNA (0.40) | LMNAHTTSMN1; SMN2JAK3AURKA | |
| SCHEMBL22564309 | 0.86 | NPC1 (0.37) | LMNASMN1; SMN2NPC1RAB9ACTSD | |
| SCHEMBL22564542 | 0.86 | NPC1 (0.37) | LMNAHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |