Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564229 | 0.92 | ALDH1A1 (0.40) | HSD17B10USP2TP53MAPK1RECQL | |
| SCHEMBL22564481 | 0.89 | RORC (0.38) | TP53KDM4EMAPTTSHRMRGPRX4 | |
| SCHEMBL18504408 | 0.88 | HSD17B10 (0.43) | HSD17B10USP2TP53MAPK1RECQL | |
| SCHEMBL22564498 | 0.87 | PDK2 (0.35) | KDM4EMAPTJMJD6PDK2NPC1 | |
| SCHEMBL22563850 | 0.86 | JMJD6 (0.44) | TP53KDM4EMAPTALDH1A1TSHR | |
| SCHEMBL22564480 | 0.86 | GABRA5 (0.39) | MRGPRX4GABRA5 | |
| SCHEMBL22564101 | 0.86 | TSHR (0.42) | HSD17B10KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL22564302 | 0.86 | SCN9A (0.40) | TP53KDM4EMAPTALDH1A1HPGD | |
| SCHEMBL22564087 | 0.85 | STIM1 (0.33) | MRGPRX4GAAGABRA5 | |
| SCHEMBL22564271 | 0.85 | AURKA (0.36) | KDM4EALDH1A1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |