Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.33 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | CD38 | P28907 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564480 | 0.90 | GABRA5 (0.39) | STIM1ORAI1MRGPRX4GABRA5RXRA | |
| SCHEMBL22564262 | 0.89 | STIM1 (0.39) | STIM1ORAI1GABRA5POLBRXFP1 | |
| SCHEMBL22564334 | 0.89 | STIM1 (0.33) | STIM1ORAI1MRGPRX4GABRA5CTNNB1 | |
| SCHEMBL22564271 | 0.89 | AURKA (0.36) | STIM1ORAI1CD38 | |
| SCHEMBL18504494 | 0.87 | STIM1 (0.34) | STIM1ORAI1MRGPRX4GABRA5CTNNB1 | |
| SCHEMBL22564481 | 0.87 | RORC (0.38) | STIM1ORAI1MRGPRX4GABRA5POLB | |
| SCHEMBL22564193 | 0.87 | LMNA (0.45) | STIM1ORAI1GABRA5POLBRXFP1 | |
| SCHEMBL22564404 | 0.86 | STIM1 (0.36) | STIM1ORAI1MRGPRX4GABRA5POLB | |
| SCHEMBL22563965 | 0.85 | HSD17B10 (0.42) | MRGPRX4GABRA5GAA | |
| SCHEMBL22564458 | 0.85 | TDP1 (0.36) | PTGER1NR1H4SGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |