Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564039 | 0.92 | ALDH1A1 (0.39) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 | |
| SCHEMBL22564303 | 0.91 | MAPT (0.40) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 | |
| SCHEMBL22563951 | 0.90 | KLKB1 (0.36) | SMN1; SMN2ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL18504422 | 0.89 | TBXAS1 (0.38) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 | |
| SCHEMBL22564213 | 0.89 | TSHR (0.40) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 | |
| SCHEMBL22564217 | 0.88 | LMNA (0.35) | SMN1; SMN2TSHRJMJD6ALDH1A1LMNA | |
| SCHEMBL22564497 | 0.88 | TBXAS1 (0.39) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 | |
| SCHEMBL22564215 | 0.88 | MAPT (0.41) | TBXAS1TSHRLMNAPOLBKDM4E | |
| SCHEMBL22563858 | 0.86 | TAS2R14 (0.35) | SMN1; SMN2ALDH1A1LMNAHCRTR1HCRTR2 | |
| SCHEMBL22563857 | 0.86 | TSHR (0.38) | TBXAS1SMN1; SMN2TSHRJMJD6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |