Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALKBH1 | Q13686 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | GUCY1B2 | O75343 | 6/20 | 0.33 |
| ▸ | GUCY1A2 | P33402 | 6/20 | 0.33 |
| ▸ | GUCY1A1 | Q02108 | 6/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564177 | 0.89 | ALKBH1 (0.39) | TDP1ALKBH1NPC1PTGER1ALDH1A1 | |
| SCHEMBL22564068 | 0.88 | SGMS2 (0.35) | TDP1ALKBH1NPC1PTGER1GUCY1B2 | |
| SCHEMBL22564082 | 0.88 | ALDH1A1 (0.42) | TDP1ALKBH1NPC1PTGER1ALDH1A1 | |
| SCHEMBL22564128 | 0.88 | KLKB1 (0.37) | TDP1ALKBH1 | |
| SCHEMBL18504735 | 0.86 | TDP1 (0.36) | TDP1ALKBH1NPC1PTGER1GUCY1B2 | |
| SCHEMBL22564350 | 0.86 | NR1H4 (0.32) | TDP1ALDH1A1L3MBTL1NR1H4 | |
| SCHEMBL22563954 | 0.86 | KMT2A (0.42) | TDP1NPC1ALDH1A1KMT2AATM | |
| SCHEMBL22563884 | 0.86 | FOLH1 (0.32) | NR1H4 | |
| SCHEMBL22564169 | 0.86 | HDAC1 (0.35) | TDP1ALKBH1NPC1GUCY1B2GUCY1A2 | |
| SCHEMBL22564022 | 0.85 | SLC22A12 (0.36) | L3MBTL1SGMS2RAB9ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |