Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | STAT3 | P40763 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22564378 | 0.91 | PDE5A (0.31) | — | |
| SCHEMBL22564127 | 0.90 | — | — | |
| SCHEMBL22564173 | 0.90 | LMNA (0.34) | SMN1; SMN2LMNANPC1HTTRAB9A | |
| SCHEMBL22563884 | 0.89 | FOLH1 (0.32) | — | |
| SCHEMBL22563845 | 0.87 | FOLH1 (0.34) | HTTALDH1A1 | |
| SCHEMBL22564152 | 0.87 | HCRTR1 (0.31) | SMN1; SMN2LMNANPC1HTTRAB9A | |
| SCHEMBL22563909 | 0.87 | ALDH1A1 (0.34) | LMNANPC1HTTRAB9ANPSR1 | |
| SCHEMBL22564084 | 0.86 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL22564506 | 0.86 | MEN1 (0.35) | KDR | |
| SCHEMBL22564068 | 0.86 | SGMS2 (0.35) | SMN1; SMN2LMNANPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841429-B1 | TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES | SUMITOMO CHEMICAL CO (JP) | 2020-10-21 | — | — | EP | disclosed |