SCHEMBL22569945

SCHEMBL22569945

CC(C#N)(CCC(=O)NCCCN=[N+]=[N-])/N=N/C(C)(C#N)CCC(=O)NCCCN=[N+]=[N-]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
USP14 P54578 1/20 0.32
CASP2 P42575 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19463227 1.00 USP14 (0.32) USP14CASP2
SCHEMBL24979274 0.81 SLC6A5 (0.37) CASP2
SCHEMBL12300506 0.77 PGK1 (0.40)
SCHEMBL15042743 0.76
SCHEMBL23530174 0.75 USP14 (0.31) USP14
SCHEMBL19560634 0.74 CASP2 (0.56) CASP2
SCHEMBL9799140 0.73 CASP2 (0.31) CASP2
SCHEMBL15044593 0.73 CNR2 (0.31)
SCHEMBL21695691 0.73 TSHR (0.33)
SCHEMBL23569090 0.72 CASP2 (0.38) CASP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230026627-A1 Compositions and Methods of Manufacturing Star Polymers for Ligand Display and/or Drug Delivery VACCITECH NORTH AMERICA, INC. (US) 2023-01-26 US disclosed
WO-2022086853-A1 STAR POLYMER DRUG CONJUGATES AVIDEA TECHNOLOGIES, INC. (US) 2022-04-28 WO disclosed
WO-2020214858-A1 COMPOSITIONS AND METHODS OF MANUFACTURING STAR POLYMERS FOR LIGAND DISPLAY AND/OR DRUG DELIVERY AVIDEA TECHNOLOGIES, INC. (US) 2020-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026627-A1 Compositions and Methods of Manufacturing Star Polymers for Ligand Display and/or Drug Delivery TNFSF10, SELPLG, FCGRT USP14 3645/4885CASP2 3373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.