SCHEMBL2257170

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2254886	0.93	ALDH1A1 (0.47)	MAPTSMN1; SMN2LMNAMAPK1TSHR
	SCHEMBL2257274	0.92	ALDH1A1 (0.45)	MAPTSMN1; SMN2LMNAPOLBTP53
	SCHEMBL2259720	0.92	TGFBR1 (0.45)	MAPTSMN1; SMN2LMNAPOLBALDH1A1
	SCHEMBL2257528	0.91	POLB (0.46)	MAPTSMN1; SMN2NPC1POLBTP53
	SCHEMBL2258161	0.90	KDM4E (0.47)	SMN1; SMN2LMNANPC1ALDH1A1TGFBR1
	SCHEMBL2256806	0.90	L3MBTL1 (0.43)	MAPTSMN1; SMN2LMNANPC1ALDH1A1
	SCHEMBL2259530	0.90	MAPT (0.45)	MAPTLMNANPC1POLBTP53
	SCHEMBL2258350	0.88	NPC1 (0.44)	MAPTSMN1; SMN2LMNAMAPK1NPC1
	SCHEMBL2262678	0.88	RAB9A (0.46)	MAPTSMN1; SMN2NPC1POLBTP53
	SCHEMBL2255675	0.88	STAT3 (0.56)	MAPTSMN1; SMN2LMNAMAPK1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.