Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.42 |
| ▸ | HTR3B | O95264 | 3/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667496 | 0.75 | CA4 (0.42) | LTA4HTSHRCA5ACA5BLMNA | |
| SCHEMBL28231065 | 0.74 | ALDH1A1 (0.41) | PARP10KMT2ALMNACYP1A2MAOA | |
| SCHEMBL8998709 | 0.73 | USP2 (0.43) | PRSS1ACRTMPRSS15PARP10KMT2A | |
| SCHEMBL14667491 | 0.71 | MAPT (0.39) | LTA4HTSHRCA5ACA5BKMT2A | |
| SCHEMBL31173462 | 0.71 | MAPT (0.39) | LTA4HTSHRCA5ACA5BKMT2A | |
| SCHEMBL9052201 | 0.70 | — | — | |
| SCHEMBL14667488 | 0.70 | CA4 (0.42) | LTA4HTSHRKMT2ALMNACYP1A2 | |
| SCHEMBL13505497 | 0.70 | CA5A (0.38) | LTA4HTSHRCA5ACA5BKMT2A | |
| SCHEMBL9175243 | 0.69 | MAPT (0.44) | KMT2AUSP2TAAR1 | |
| SCHEMBL12057067 | 0.69 | L3MBTL1 (0.37) | LTA4HTSHRKMT2ALMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356457-B1 | METHOD FOR THE PREPARATION OF IMMUNOCONJUGATES AND USE THEREOF | XEPTAGEN SPA (IT) | 2018-05-16 | — | — | EP | disclosed |
| US-20110207155-A1 | Method for the preparation of immunoconjugates and use thereof | XEPTAGEN SPA (IT) | 2011-08-25 | — | — | US | disclosed |
| EP-2356457-A1 | METHOD FOR THE PREPARATION OF IMMUNOCONJUGATES AND USE THEREOF | Xeptagen SPA (IT) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010043927-A1 | METHOD FOR THE PREPARATION OF IMMUNOCONJUGATES AND USE THEREOF | XEPTAGEN SPA (IT) | 2010-04-22 | — | — | WO | disclosed |
| US-5292755-A | USPA benzolyguanidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-08 | — | — | US | disclosed |
| EP-0173320-A1 | Substituted carbonylphenylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173319-A1 | Substituted arylsulfonyl guanidines | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0173321-A1 | Sulfonyl-guanidinopyrimidine derivatives | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |