SCHEMBL9175243

SCHEMBL9175243

CC(=O)C(C)=NOc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
ALDH1A1 P00352 2/20 0.44
MTNR1A P48039 5/20 0.42
MTNR1B P49286 5/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
MAOB P27338 1/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
EPHX1 P07099 1/20 0.40
ACACB O00763 1/20 0.39
ACACA Q13085 1/20 0.39
USP2 O75604 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSP90AA1 P07900 1/20 0.39
GAA P10253 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
HSD17B10 Q99714 1/20 0.39
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9676833 0.82 MAPT (0.45) MAPTALDH1A1MTNR1AMTNR1BL3MBTL1
SCHEMBL9254279 0.82 CES2 (0.50) MAPTALDH1A1L3MBTL1MAOBCES2
SCHEMBL15301220 0.82 LMNA (0.50) MAPTALDH1A1L3MBTL1MAOBCES2
SCHEMBL14667496 0.78 CA4 (0.42) MAPTALDH1A1MTNR1AMTNR1BL3MBTL1
SCHEMBL11316500 0.74 ALDH1A1 (0.43) MAPTALDH1A1MTNR1AMTNR1BL3MBTL1
SCHEMBL14667491 0.74 MAPT (0.39) MAPTALDH1A1L3MBTL1MAOBUSP2
SCHEMBL31173462 0.74 MAPT (0.39) MAPTALDH1A1L3MBTL1MAOBUSP2
SCHEMBL6296504 0.73 GAA (0.43) MAPTALDH1A1L3MBTL1MAOBUSP2
SCHEMBL14667488 0.72 CA4 (0.42) MAPTALDH1A1MTNR1AMTNR1BL3MBTL1
SCHEMBL194740 0.72 SMN1; SMN2 (0.59) MAPTALDH1A1L3MBTL1CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0377321-B1 Photopolymerizable composition FUJI PHOTO FILM CO LTD (JP) 1995-03-22 EP claimed
CN-117165089-A Photocurable black silicone composition and cured product thereof 罗门哈斯电子材料韩国有限公司 2023-12-05 CN disclosed