Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23135865 | 0.88 | LMNA (0.43) | LMNANPSR1POLBCA1CA2 | |
| SCHEMBL23913202 | 0.86 | CA2 (0.39) | LMNATGM2NPSR1POLBCA1 | |
| SCHEMBL24311588 | 0.85 | CA1 (0.39) | LMNATGM2NPSR1POLBCA1 | |
| SCHEMBL20381796 | 0.82 | LMNA (0.42) | LMNATGM2NPSR1POLBCA1 | |
| SCHEMBL21078459 | 0.80 | CA2 (0.41) | LMNANPSR1POLBCA1CA2 | |
| SCHEMBL24677753 | 0.79 | LMNA (0.47) | LMNANPSR1POLBCA1CA2 | |
| SCHEMBL19308088 | 0.73 | FBP1 (0.33) | LMNASMN1; SMN2RAB9A | |
| SCHEMBL15172248 | 0.72 | LIMK1 (0.46) | LMNANPSR1CA1CA2CA12 | |
| SCHEMBL29191945 | 0.68 | LMNA (0.59) | LMNACA1CA2CA12CA4 | |
| SCHEMBL14368127 | 0.68 | CA1 (0.55) | LMNACA1CA2ALDH1A1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10842152-B2 | Isothiazolo-based bicycles, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-11-24 | — | — | US | disclosed |
| US-20200331904-A1 | 3-AMINO-[1,2,4]-TRIAZOLE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10842152-B2 | Isothiazolo-based bicycles, processes for their preparation and their use as herbicides and/or plant growth regulators | ING2, DDT, CBR3 | LMNA 4853/4885TGM2 2109/4885NPSR1 3128/4885 |
| US-20200331904-A1 | 3-AMINO-[1,2,4]-TRIAZOLE DERIVATIVES AND THEIR USE FOR CONTROLLING UNDESIRED PLANT GROWTH | NAT1, AGXT, CYP4Z1 | LMNA 4825/4885TGM2 339/4885NPSR1 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.