SCHEMBL22586096

SCHEMBL22586096

FC(F)(F)c1cc(-c2ccc3c(c2)c2cc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)ccc2n3-c2ccc(-c3ccc4c5ccccc5n(-c5ccccc5)c4c3)cc2-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)cc(C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ABCG2 Q9UNQ0 4/20 0.33
ICMT O60725 3/20 0.33
LMNA P02545 2/20 0.33
POLB P06746 1/20 0.33
PTGER4 P35408 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
ALDH1A1 P00352 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TACR1 P25103 1/20 0.31
NR3C1 P04150 1/20 0.31
PGR P06401 1/20 0.31
MGLL Q99685 1/20 0.31
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22586551 1.00 MAT2A (0.34) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22586549 1.00 MAT2A (0.34) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22586742 0.97 ATM (0.36) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22586542 0.97 KDM4E (0.36) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22586559 0.97 KDM4E (0.36) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22587036 0.95 MAT2A (0.32) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL25945099 0.95 PTGER4 (0.33) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL25945496 0.94 MAT2A (0.34) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22585945 0.92 MAT2A (0.41) MAT2AKDM4EATML3MBTL1ABCG2
SCHEMBL22586250 0.92 MAT2A (0.39) MAT2AKDM4EATML3MBTL1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230278992-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-07 US disclosed
US-11718608-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-08 US disclosed
US-11718608-B2 Organic molecules for use in optoelectronic devices SAMSUNG DISPLAY CO., LTD. (KR) 2023-08-08 US disclosed
US-20200331898-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718608-B2 Organic molecules for use in optoelectronic devices OR10J3, AOX1, ALDH1A2 MAT2A 1221/4885KDM4E 3834/4885ATM 3544/4885
US-20230278992-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, AOX1, ALDH1A2 MAT2A 1097/4885KDM4E 3938/4885ATM 3535/4885
US-20200331898-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OPRM1, ORC3 MAT2A 1605/4885KDM4E 1821/4885ATM 3440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.