SCHEMBL225997

SCHEMBL225997

CCCCCCC1(C#N)C=CC(c2ccccc2)C=C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
MMP2 P08253 4/20 0.35
MMP9 P14780 4/20 0.35
MMP3 P08254 1/20 0.35
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.33
GLA P06280 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.32
KDM1A O60341 1/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5718629 1.00 MEN1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL4476022 1.00 MEN1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL8339744 1.00 MEN1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL9747316 1.00 MEN1 (0.36) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL407033 0.99 ALDH1A1 (0.34) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL10604204 0.94 SLC10A2 (0.34) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL9846940 0.92 MMP2 (0.40) MEN1KMT2AALDH1A1SMN1; SMN2HIF1A
SCHEMBL9689895 0.91 MMP2 (0.38) MMP2MMP9MMP3
SCHEMBL8377636 0.88 KDM1A (0.38) MEN1KMT2AALDH1A1GAAKDM4E
SCHEMBL3480926 0.82 KDM1A (0.35) MEN1KMT2AALDH1A1GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117901461-A Multimode dual-signal sensing film and preparation method thereof 河北工业大学 2024-04-19 CN claimed
CN-113296310-A Quantum dot light conversion layer and preparation method thereof 广东普加福光电科技有限公司 2021-08-24 CN claimed
CN-100365096-C Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2008-01-30 CN claimed
CN-1753969-A Nematic liquid crystal mixtures for bistable display devices NEMOPTIC (FR) 2006-03-29 CN claimed
CN-118235072-A Optical film and polarizing plate 东曹株式会社 2024-06-21 CN disclosed
CN-111139117-B Lubricant composition containing an anti-flaking agent 协同油脂株式会社 2023-03-24 CN disclosed
CN-113296310-A Quantum dot light conversion layer and preparation method thereof 广东普加福光电科技有限公司 2021-08-24 CN disclosed
CN-111139117-A Anti-flaking agent and lubricant composition containing same 协同油脂株式会社 2020-05-12 CN disclosed
US-10344320-B2 Capacitive liquid crystal biosensors THE JOHNS HOPKINS UNIVERSITY (US) 2019-07-09 US disclosed
US-20160327506-A1 CAPACITIVE LIQUID CRYSTAL BIOSENSORS THE JOHNS HOPKINS UNIVERSITY 2016-11-10 US disclosed
CN-102933691-B Switching element comprising a liquid-crystalline medium MERCK PATENT GMBH 2015-05-20 CN disclosed
CN-102892862-B Optical switch element comprising a liquid-crystalline medium MERCK PATENT GMBH 2015-05-13 CN disclosed
EP-0903383-A1 Hot melt ink compositions Xerox Corporation (US) 1999-03-24 EP disclosed
EP-0488708-B1 Optical switching device FUJITSU LTD (JP) 1997-01-29 EP disclosed
US-5317429-A Trilayer nematic liquid crystal optical switching device FUJITSU LIMITED (JP) 1994-05-31 US disclosed
EP-0488708-A2 Optical switching device FUJITSU LIMITED (JP) 1992-06-03 EP disclosed
CN-1051926-A ELECTROOPTIC LIQUID CRYSTAL SYSTEM MERCK PATENT GES MIT BESSCHRAN (DE) 1991-06-05 CN disclosed
EP-0366985-A1 Super twist liquid crystal display MERCK PATENT GmbH (DE) 1990-05-09 EP disclosed
EP-0325796-A1 A liquid crystal compound and a mixture containing the same Chisso Corporation (JP) 1989-08-02 EP disclosed
US-4583826-A Phenylethanes HOFFMANN-LA ROCHE INC. (US) 1986-04-22 US disclosed