SCHEMBL9689895

SCHEMBL9689895

CCCCCC1(C#N)C=CC(c2ccc(-c3ccccc3)cc2)C=C1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 3/20 0.38
MMP9 P14780 3/20 0.38
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
NCOR2 Q9Y618 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MGAT2 Q10469 1/20 0.31
SOAT1 P35610 2/20 0.31
POLB P06746 1/20 0.31
MMP3 P08254 1/20 0.30
HSD11B1 P28845 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846940 0.99 MMP2 (0.40) MMP2MMP9HDAC3HDAC1HDAC2
SCHEMBL407033 0.92 ALDH1A1 (0.34) MMP2MMP9MMP3SIGMAR1
SCHEMBL5718629 0.91 MEN1 (0.36) MMP2MMP9MMP3
SCHEMBL4476022 0.91 MEN1 (0.36) MMP2MMP9MMP3
SCHEMBL9747316 0.91 MEN1 (0.36) MMP2MMP9MMP3
SCHEMBL225997 0.91 MEN1 (0.36) MMP2MMP9MMP3
SCHEMBL8339744 0.91 MEN1 (0.36) MMP2MMP9MMP3
SCHEMBL10604204 0.88 SLC10A2 (0.34)
SCHEMBL8377636 0.82 KDM1A (0.38) TSHRHSD17B10
SCHEMBL9846952 0.76 KDM4E (0.33) MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9690161-B2 Field induced heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-06-27 US claimed
US-20160033806-A1 FIELD INDUCED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-02-04 US claimed
CN-117157337-A Fumaric acid diester resin, film and polarizing plate 东曹株式会社 2023-12-01 CN disclosed
CN-111139117-A Anti-flaking agent and lubricant composition containing same 协同油脂株式会社 2020-05-12 CN disclosed
US-9732277-B2 Field induced and controlled heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-08-15 US disclosed
US-9690161-B2 Field induced heliconical structure of cholesteric liquid crystal KENT STATE UNIVERSITY (US) 2017-06-27 US disclosed
US-20160252755-A1 FIELD INDUCED AND CONTROLLED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-09-01 US disclosed
US-20160033806-A1 FIELD INDUCED HELICONICAL STRUCTURE OF CHOLESTERIC LIQUID CRYSTAL KENT STATE UNIVERSITY 2016-02-04 US disclosed
EP-0472403-A2 Microwave phase modulation with liquid crystals Hughes Aircraft Company (US) 1992-02-26 EP disclosed
EP-0415220-A2 Chiral doping agents for liquid crystals F. HOFFMANN-LA ROCHE AG (CH) 1991-03-06 EP disclosed
EP-0407830-A2 Polarizer F. HOFFMANN-LA ROCHE AG (CH) 1991-01-16 EP disclosed
EP-0359801-A1 ACRYLATE POLYMER-DISPERSED LIQUID CRYSTAL MATERIAL AND DEVICES MADE THEREFROM. HUGHES AIRCRAFT CO (US) 1990-03-28 EP disclosed
WO-1989006371-A2 ACRYLATE POLYMER-DISPERSED LIQUID CRYSTAL MATERIAL AND DEVICES MADE THEREFROM HUGHES AIRCRAFT COMPANY (US) 1989-07-13 WO disclosed
EP-0304738-A2 Optically active liquid-crystal components F. HOFFMANN-LA ROCHE AG (CH) 1989-03-01 EP disclosed