Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924912 | 0.96 | POLB (0.49) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL17433312 | 0.85 | THRB (0.53) | POLBAPEX1HTTTDP1ALDH1A1 | |
| SCHEMBL10457799 | 0.85 | THRB (0.50) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL18820317 | 0.84 | POLB (0.48) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL17036777 | 0.83 | POLB (0.58) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL26362183 | 0.83 | THRB (0.57) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL22566483 | 0.83 | THRB (0.57) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL20614307 | 0.83 | THRB (0.52) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL12092909 | 0.82 | ELANE (0.47) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL7918640 | 0.82 | POLB (0.45) | POLBAPEX1HTTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339884-A1 | LIQUID CRYSTAL COMPOSITION AND USE THEREOF | JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |