Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22600438 | 0.96 | POLB (0.46) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL17036777 | 0.87 | POLB (0.58) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL7918640 | 0.86 | POLB (0.45) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL7918643 | 0.84 | KDM4E (0.46) | POLBAPEX1HTTTDP1NPC1 | |
| SCHEMBL17036971 | 0.84 | POLB (0.63) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL11921516 | 0.83 | THRB (0.55) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL17036987 | 0.83 | POLB (0.55) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL10029272 | 0.83 | POLB (0.58) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL28035136 | 0.83 | POLB (0.55) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL22566492 | 0.82 | THRB (0.53) | POLBAPEX1HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6231714-B1 | BONDING PAIR OF SUBSTRATES | LOCTITE CORPORATION | 2001-05-15 | — | — | US | claimed |
| WO-2000032550-A1 | ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS | LOCTITE CORPORATION (US) | 2000-06-08 | — | — | WO | claimed |
| US-6231714-B1 | BONDING PAIR OF SUBSTRATES | LOCTITE CORPORATION | 2001-05-15 | — | — | US | disclosed |
| WO-2000032550-A1 | ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS | LOCTITE CORPORATION (US) | 2000-06-08 | — | — | WO | disclosed |