SCHEMBL7918640

SCHEMBL7918640

C=CCOc1ccc(COC(=O)C(=C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
MAPT P10636 3/20 0.43
NPC1 O15118 3/20 0.43
RAB9A P51151 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
USP2 O75604 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CACNA1B Q00975 1/20 0.43
APBA1 Q02410 1/20 0.43
TP53 P04637 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8421684 0.86 ALDH1A1 (0.51) POLBMAPTNPC1RAB9AMEN1
SCHEMBL7924912 0.86 POLB (0.49) POLBAPEX1HTTTDP1MAPT
SCHEMBL12053095 0.85 CNR1 (0.40) POLBAPEX1HTTTDP1MAPT
SCHEMBL7924216 0.83 KDM4E (0.48) NPC1RAB9AALDH1A1FFAR1ADRB2
SCHEMBL455205 0.83 ALDH1A1 (0.49) POLBAPEX1HTTTDP1MAPT
SCHEMBL22600438 0.82 POLB (0.46) POLBAPEX1HTTTDP1MAPT
SCHEMBL254038 0.82 ALDH1A1 (0.50) POLBAPEX1HTTTDP1MEN1
SCHEMBL4533571 0.81 ELANE (0.51) POLBAPEX1HTTTDP1MAPT
SCHEMBL10904059 0.81 POLB (0.44) POLBAPEX1HTTTDP1MAPT
SCHEMBL28756540 0.81 POLB (0.52) POLBAPEX1HTTTDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US claimed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO claimed
CN-118459679-A Method for preparing composite micelles and nanogels with different morphologies by using electrostatic template polymerization method 雅图诺生物科技南通有限公司 2024-08-09 CN disclosed
CN-114716604-B Production process of electronic resin material 重庆市化工研究院有限公司 2023-03-21 CN disclosed
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US disclosed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO disclosed