Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22601485 | 0.85 | TNKS (0.41) | CYP3A4HTTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL22601489 | 0.74 | LMNA (0.41) | CYP3A4HTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL22601482 | 0.69 | CYP3A4 (0.35) | CYP3A4LMNAPOLBHPGDMEN1 | |
| SCHEMBL3466137 | 0.68 | KMT2A (0.44) | CYP3A4HTTSMN1; SMN2NPSR1LMNA | |
| SCHEMBL18645889 | 0.64 | MAPT (0.42) | CYP3A4HTTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL15954596 | 0.64 | MAPT (0.45) | CYP3A4HTTSMN1; SMN2CYP1A2LMNA | |
| SCHEMBL14653418 | 0.63 | PARP14 (0.42) | CYP3A4CYP1A2LMNAPOLBHPGD | |
| SCHEMBL25873153 | 0.63 | ALDH1A1 (0.39) | CYP3A4HTTSMN1; SMN2LMNAPOLB | |
| SCHEMBL808125 | 0.63 | GPR3 (0.61) | SMN1; SMN2CYP1A2POLBHPGDMAPT | |
| SCHEMBL16218710 | 0.62 | CYP3A4 (0.44) | CYP3A4HTTSMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200343456-A1 | Fused Polycyclic Compound, and Preparation Method and Use Thereof | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200343456-A1 | Fused Polycyclic Compound, and Preparation Method and Use Thereof | INTS9, INF2, CYBA | CYP3A4 265/4885HTT 61/4885SMN1; SMN2 3171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.