Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.33 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25873178 | 0.90 | ALDH1A1 (0.39) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL25873100 | 0.81 | TSHR (0.39) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL16218710 | 0.79 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL25873072 | 0.78 | MAPT (0.39) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL22607155 | 0.77 | DHFR (0.39) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL16218719 | 0.76 | CYP3A4 (0.44) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL14951426 | 0.76 | S100A4 (0.41) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL16218713 | 0.76 | PARP14 (0.43) | CYP3A4MEN1MAPTKMT2ALMNA | |
| SCHEMBL22601485 | 0.75 | TNKS (0.41) | ALDH1A1CYP3A4TSHRMEN1MAPT | |
| SCHEMBL22601474 | 0.75 | CYP3A4 (0.40) | CYP3A4TSHRMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | NINGBO LUMILAN ADVANCED MATERIALS CO., LTD. (CN) | 2023-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11706982-B2 | Fused polycyclic compound, and preparation method and use thereof | INF2, INTS9, PYM1 | ALDH1A1 3407/4885CYP3A4 322/4885TSHR 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.