Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.68 |
| ▸ | RAB9A | P51151 | 5/20 | 0.68 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | HMGCR | P04035 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38652178 | 1.00 | NPC1 (0.68) | NPC1RAB9AHSP90AB1HPGDCYP3A4 | |
| SCHEMBL3709147 | 1.00 | NPC1 (0.68) | NPC1RAB9AHSP90AB1HPGDCYP3A4 | |
| SCHEMBL5477586 | 0.87 | NPC1 (0.70) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL3658652 | 0.86 | NPC1 (0.64) | NPC1RAB9AHSP90AB1HPGDCYP3A4 | |
| SCHEMBL8665984 | 0.86 | NPC1 (0.63) | NPC1RAB9AHSP90AB1HPGDCYP3A4 | |
| SCHEMBL28085535 | 0.85 | NPC1 (0.53) | NPC1RAB9AHSP90AB1HPGDCYP3A4 | |
| SCHEMBL3048417 | 0.84 | NPC1 (0.66) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL30263100 | 0.84 | NPC1 (0.66) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL1938819 | 0.84 | NPC1 (0.68) | NPC1RAB9AHPGDCYP3A4ALDH1A1 | |
| SCHEMBL5624874 | 0.84 | RAB9A (0.66) | NPC1RAB9AHPGDCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114146071-B | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2023-02-28 | — | — | CN | claimed |
| CN-114146071-A | Application of paeonol and its derivatives in preventing and treating leukoplakia syndrome | 西北农林科技大学深圳研究院 | 2022-03-08 | — | — | CN | claimed |
| CN-106727455-A | Application of the Paeonol in preparing for preventing, treating the abnormal medicine for increasing disease of TOPK activity | 史飞 | 2017-05-31 | — | — | CN | claimed |
| CN-105136960-B | A kind of method of detection and discriminating donkey, horse or Corii Bovis seu Bubali odour component and judging standard thereof | 山东中医药大学 | 2016-06-22 | — | — | CN | claimed |
| CN-105136960-A | Method for detecting and distinguishing odor components of donkey hide, horse hide or cattle hide as well as distinguishing standard thereof | UNIV SHANDONG TRADITIONAL CHINESE MEDICINE | 2015-12-09 | — | — | CN | claimed |
| CN-103539268-A | Environment-friendly seawater corrosion inhibitor and application thereof | NO 725 RES INST CHINA CSIC | 2014-01-29 | — | — | CN | claimed |
| EP-4126835-B1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2026-02-18 | — | — | EP | disclosed |
| EP-4251708-B1 | METHOD FOR PRODUCING A HIGH-PHENOLIC-CONTENT BIOOIL | THE UNIV OF NEW BRUNSWICK (CA) | 2026-02-11 | — | — | EP | disclosed |
| US-12516038-B2 | Inhibitors of antigen presentation by HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2026-01-06 | — | — | US | disclosed |
| US-20250250613-A1 | DISCOVERY OF BACTERIAL AIEGEN THAT LIGHTS UP SPECIFIC G-QUADRUPLEXES | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2025-08-07 | — | — | US | disclosed |
| US-20230365764-A1 | METHOD FOR PRODUCING A HIGH-PHENOLIC-CONTENT BIOOIL | THE UNIVERSITY OF NEW BRUNSWICK (CA) | 2023-11-16 | — | — | US | disclosed |
| CN-114790159-B | Diphenyl ketone selenoethyl compound and preparation method and application thereof | 合肥学院 | 2023-08-11 | — | — | CN | disclosed |
| US-20230150985-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | JANSSEN PHARMACEUTICA NV (BE) | 2023-05-18 | — | — | US | disclosed |
| EP-1757599-A1 | INDOLE DERIVATIVES HAVING PIPERIDINE RINGS | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| EP-1757599-A1 | INDOLE DERIVATIVES HAVING PIPERIDINE RINGS | Eisai R&D Management Co., Ltd. (JP) | 2007-02-28 | — | — | EP | disclosed |
| US-20050256103-A1 | Indole derivative having piperidine ring | EISAI CO., LTD. | 2005-11-17 | — | — | US | disclosed |
| US-5786374-A | FUNGICIDES, MICROBIOCIDES | NOVARTIS CORPORATION (US) | 1998-07-28 | — | — | US | disclosed |
| WO-1996014305-A1 | BENZISOXAZOLE DERIVATIVES AND PESTICIDAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 1996-05-17 | — | — | WO | disclosed |
| US-5409952-A | Anticancer agents | ADIR ET COMPAGNIE (FR) | 1995-04-25 | — | — | US | disclosed |
| EP-0454587-A1 | Heterocyclic derivatives: 2-styryl-4H-1-benzopyran-4-ons, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-10-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150985-A1 | INHIBITORS OF ANTIGEN PRESENTATION BY HLA-DR | HLA-DRB1, CD74, HLA-C | NPC1 196/4885RAB9A 2175/4885HSP90AB1 100/4885 |
| US-20050256103-A1 | Indole derivative having piperidine ring | HTR5A, HTR2C, HTR1A | NPC1 1683/4885RAB9A 1871/4885HSP90AB1 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.