SCHEMBL2260381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15004806	0.83	PGR (0.48)	PGRPDK2PDK4MAOBPDK1
	SCHEMBL4812028	0.81	PGR (0.47)	PGRPDK2PDK4MAOBPDE3B
	SCHEMBL30642187	0.79	PDK2 (0.50)	PGRPDK2PDK4MAOBPDE3B
	SCHEMBL31381642	0.78	PDK2 (0.52)	PGRPDK2PDK4MAOBPDK1
	SCHEMBL3865185	0.78	PDK2 (0.52)	PGRPDK2PDK4MAOBPDK1
	SCHEMBL31727513	0.76	HTR6 (0.41)	PGRADRA2CTACR2ADRA1DHTR2A
	SCHEMBL15004747	0.76	PGR (0.45)	PGRPDK2PDK4AR
	SCHEMBL31381799	0.74	PGR (0.41)	PGRPDK2PDK4
	SCHEMBL24690660	0.71	PGR (0.45)	PGRPDK2PDK4MAOBPDE3B
	SCHEMBL31727696	0.70	ADRA2C (0.33)	PGRADRA2CTACR2ADRA1DHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.