Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178205 | 0.94 | EPHX1 (0.39) | EPHX1GABRR1 | |
| SCHEMBL22546507 | 0.83 | — | — | |
| SCHEMBL20876415 | 0.83 | — | — | |
| SCHEMBL1076013 | 0.83 | — | — | |
| SCHEMBL29012798 | 0.83 | — | — | |
| SCHEMBL3918742 | 0.82 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL13533362 | 0.80 | EPHX1 (0.45) | EPHX1 | |
| SCHEMBL1659517 | 0.78 | LMNA (0.38) | EPHX1 | |
| SCHEMBL277846 | 0.76 | EPHX1 (0.50) | EPHX1GABRR1 | |
| SCHEMBL38651938 | 0.76 | EPHX1 (0.50) | EPHX1GABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020216240-A1 | DICYCLIC ALKANE COMPOUND USEFUL AS INHIBITOR OF PLASMA KALLIKREIN | 南京明德新药研发有限公司 | 2020-10-29 | — | — | WO | disclosed |