Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178205 | 0.83 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL22604587 | 0.78 | EPHX1 (0.39) | EPHX1 | |
| SCHEMBL3918742 | 0.73 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL13533362 | 0.71 | EPHX1 (0.45) | EPHX1 | |
| SCHEMBL15772906 | 0.70 | GRM4 (0.54) | LMNAKDM4EHDAC4TSHR | |
| SCHEMBL27594768 | 0.68 | PSEN1 (0.40) | LMNAKDM4EHDAC4HDAC8HDAC6 | |
| SCHEMBL28236109 | 0.64 | CHRNB2 (0.38) | CYP3A4TSHREPHX1PSEN1PSEN2 | |
| SCHEMBL3936753 | 0.64 | POLB (0.44) | KDM4ECYP3A4 | |
| SCHEMBL277846 | 0.64 | EPHX1 (0.50) | LMNAKDM4EEPHX1PSEN1PSEN2 | |
| SCHEMBL20876415 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8709450-B2 | Cellulose derivative and hydrogel thereof | TEIJIN LIMITED (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20110178184-A1 | HYDROGEL | TEIJIN LIMITED (JP) | 2011-07-21 | — | — | US | disclosed |
| CN-102112496-A | Hydrogel | TEIJIN LTD | 2011-06-29 | — | — | CN | disclosed |
| US-20110129505-A1 | CELLULOSE DERIVATIVE AND HYDROGEL THEREOF | TEIJIN LIMITED (JP) | 2011-06-02 | — | — | US | disclosed |
| EP-2311883-A1 | HYDROGEL | Teijin Limited (JP) | 2011-04-20 | — | — | EP | disclosed |
| EP-2236522-A1 | CELLULOSE DERIVATIVE AND HYDROGEL THEREOF | Teijin Limited (JP) | 2010-10-06 | — | — | EP | disclosed |
| US-20100184952-A1 | METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE | AJINOMOTO CO., INC (JP) | 2010-07-22 | — | — | US | disclosed |
| EP-2181983-A1 | METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2010-05-05 | — | — | EP | disclosed |
| US-6632807-B1 | (2R,4S)-(−)-[N-(4-diethoxyphosphorylmethyl)phenyl]-1,2,4,5- tetrahydro-4-methyl-7,8-methylenedioxy-5-oxo-3-benzothiepin-2-carboxamide | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| US-6346521-B1 | OSTEOGENESIS PROMOTERS FOR BONE DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-12 | — | — | US | disclosed |
| EP-0719782-B1 | Optically active benzothiepin derivative, its preparation and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-04 | — | — | EP | disclosed |
| US-5952512-A | Production of optically active benzothiepin salts | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-14 | — | — | US | disclosed |
| EP-0842179-A1 | PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS | Takeda Chemical Industries, Ltd. (JP) | 1998-05-20 | — | — | EP | disclosed |
| EP-0585913-B1 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5700810-A | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| WO-1997003989-A1 | PRODUCTION OF OPTICALLY ACTIVE BENZOTHIEPIN SALTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |
| EP-0719782-A1 | Optically active benzothiepin derivative, its preparation and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| US-5482967-A | LOWERING CHOLESTEROL | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-09 | — | — | US | disclosed |
| EP-0585913-A2 | Condensed heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129505-A1 | CELLULOSE DERIVATIVE AND HYDROGEL THEREOF | F12, H1-4, H1-3 | LMNA 3411/4885KDM4E 475/4885HDAC4 1356/4885 |
| US-20100184952-A1 | METHOD FOR SELECTIVE REMOVAL OF DIBENZOFULVENE DERIVATIVE | DDC, DNPEP, DBF4 | LMNA 1517/4885KDM4E 36/4885HDAC4 2191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.