Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | AGER | Q15109 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432000 | 0.82 | CYP3A4 (0.46) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1727285 | 0.81 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2257060 | 0.76 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL2255791 | 0.73 | HRH3 (0.43) | RAB9ANPC1SMN1; SMN2MAPTSTAT3 | |
| SCHEMBL2257961 | 0.71 | HRH3 (0.48) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1726397 | 0.71 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2258303 | 0.71 | RAB9A (0.68) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL2904434 | 0.68 | ALDH1A3 (0.54) | RAB9ANPC1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL1727327 | 0.68 | HRH3 (0.57) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL1726214 | 0.68 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022207-B2 | Compound having affinity to amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-20110201808-A1 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2011-08-18 | — | — | US | disclosed |
| EP-2022792-B1 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID | NIHON MEDIPHYSICS CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-20100249408-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| US-20100249407-A1 | Novel Compound Having Affinity to Amyloid | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2216051-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | Nihon Medi-Physics Co., Ltd. (JP) | 2010-08-11 | — | — | EP | disclosed |
| EP-2022792-A1 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2009-02-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201808-A1 | NOVEL COMPOUND HAVING AFFINITY TO AMYLOID | APBA1, APP, BACE1 | RAB9A 1098/4885NPC1 52/4885SMN1; SMN2 609/4885 |
| US-20100249408-A1 | USE OF NOVEL COMPOUND HAVING AFFINITY FOR AMYLOID, AND PROCESS FOR PRODUCTION OF THE SAME | APBA1, APP, S100A4 | RAB9A 2369/4885NPC1 580/4885SMN1; SMN2 876/4885 |
| US-20100249407-A1 | Novel Compound Having Affinity to Amyloid | APBA1, APP, BACE1 | RAB9A 1098/4885NPC1 52/4885SMN1; SMN2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.