Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
| ▸ | ATXN2 | Q99700 | 9/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.34 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21323023 | 0.92 | ENPP2 (0.51) | ENPP2DGAT2ATXN2KCNK3KCNK9 | |
| SCHEMBL16963143 | 0.92 | ENPP2 (0.51) | ENPP2DGAT2ATXN2KCNK3KCNK9 | |
| SCHEMBL16963033 | 0.88 | ENPP2 (0.57) | ENPP2DGAT2ATXN2LIPEGHSR | |
| SCHEMBL21323097 | 0.88 | ENPP2 (0.57) | ENPP2DGAT2ATXN2LIPEGHSR | |
| SCHEMBL16963383 | 0.88 | ENPP2 (0.57) | ENPP2DGAT2ATXN2LIPEGHSR | |
| SCHEMBL16963684 | 0.88 | ENPP2 (0.57) | ENPP2DGAT2ATXN2LIPEGHSR | |
| SCHEMBL21323020 | 0.85 | ENPP2 (0.49) | ENPP2DGAT2ATXN2TLR9TLR8 | |
| SCHEMBL16962689 | 0.85 | ENPP2 (0.49) | ENPP2DGAT2ATXN2TLR9TLR8 | |
| SCHEMBL16962688 | 0.85 | ENPP2 (0.49) | ENPP2DGAT2ATXN2TLR9TLR8 | |
| SCHEMBL21323238 | 0.84 | ENPP2 (0.48) | ENPP2DGAT2ATXN2LIPEFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339570-A1 | BICYCLIC DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2020-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339570-A1 | BICYCLIC DERIVATIVES | CCNY, BICRA, UQCRB | ENPP2 1716/4885DGAT2 3583/4885ATXN2 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.