Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SLC26A6 | Q9BXS9 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609253 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HTTSLC26A6POLBKMT2A | |
| SCHEMBL22609335 | 0.81 | HTT (0.45) | ALDH1A1HTTMAPTGABRA5POLB | |
| SCHEMBL20510965 | 0.76 | CA1 (0.51) | ALDH1A1MAPTGABRA5POLBKMT2A | |
| SCHEMBL22609248 | 0.74 | ALDH1A1 (0.38) | ALDH1A1HTTMAPTGABRA5KMT2A | |
| SCHEMBL15529175 | 0.72 | MAPT (0.57) | ALDH1A1HTTSLC26A6MAPTKMT2A | |
| SCHEMBL19893301 | 0.71 | SMN1; SMN2 (0.35) | ALDH1A1MAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL23486276 | 0.70 | MAPT (0.46) | MAPTPOLBKMT2ASMN1; SMN2VNN1 | |
| SCHEMBL31226160 | 0.69 | NPSR1 (0.45) | ALDH1A1HTTMAPTPOLBKMT2A | |
| SCHEMBL23453702 | 0.69 | VNN1 (0.46) | HTTMAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL22609257 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HTTMAPTPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | ORFAN BIOTECH SL (ES) | 2021-06-10 | — | — | US | disclosed |
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171503-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | PNPO, XDH, GLS | ALDH1A1 149/4885HTT 4735/4885SLC26A6 1148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.