Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 4/20 | 0.43 |
| ▸ | FABP7 | O15540 | 3/20 | 0.43 |
| ▸ | FABP3 | P05413 | 3/20 | 0.43 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23453734 | 0.79 | SYK (0.43) | GSK3AMAOBXDHMAOA | |
| SCHEMBL23453756 | 0.75 | CSF1R (0.40) | GSK3AGSK3BKDM4EPTGER4 | |
| SCHEMBL22609280 | 0.71 | GSK3A (0.42) | GSK3AGSK3BKDM4E | |
| SCHEMBL13758180 | 0.70 | HDAC1 (0.63) | FABP5FABP7FABP3PRKACACDK8 | |
| SCHEMBL22609306 | 0.65 | RAPGEF4 (0.48) | — | |
| SCHEMBL10401317 | 0.65 | ACMSD (0.58) | FABP5FABP7FABP3MAOBXDH | |
| SCHEMBL22609217 | 0.64 | KDM1A (0.43) | MAOBMAOAKDM4E | |
| SCHEMBL1316514 | 0.63 | CYP11B2 (0.52) | FABP5FABP7FABP3CDK8XDH | |
| SCHEMBL2352315 | 0.63 | TSHR (0.54) | MAOBCYP11B1CYP11B2MAOAKDM4E | |
| SCHEMBL19373008 | 0.63 | TSHR (0.54) | MAOBCYP11B1CYP11B2MAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |