Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.52 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.51 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | FABP7 | O15540 | 1/20 | 0.51 |
| ▸ | FABP3 | P05413 | 1/20 | 0.51 |
| ▸ | XDH | P47989 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 2/20 | 0.45 |
| ▸ | CDK8 | P49336 | 2/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.44 |
| ▸ | STK16 | O75716 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315497 | 0.90 | MEN1 (0.51) | CYP11B2CYP11B1SCN10AKCNH2XDH | |
| SCHEMBL1315751 | 0.81 | ACLY (0.64) | HDAC1HDAC2HDAC3XDHKAT6A | |
| SCHEMBL31243011 | 0.79 | CYP11B2 (0.52) | CYP11B2CYP11B1SCN10AKCNH2XDH | |
| SCHEMBL6833755 | 0.78 | KCNH2 (0.55) | HDAC1SCN10AKCNH2XDHKAT6A | |
| SCHEMBL12118152 | 0.77 | ACLY (0.59) | HDAC1HDAC2HDAC3XDHABCB1 | |
| SCHEMBL27847091 | 0.77 | HDAC1 (0.59) | HDAC1SCN10AHDAC2HDAC3KAT6A | |
| SCHEMBL12118131 | 0.76 | ACLY (0.58) | HDAC1SCN10AKCNH2HDAC2HDAC3 | |
| SCHEMBL12118188 | 0.76 | HDAC1 (0.62) | HDAC1KCNH2HDAC2HDAC3ABCB1 | |
| SCHEMBL1316860 | 0.76 | ACLY (0.58) | HDAC1HDAC2HDAC3XDHABCB1 | |
| SCHEMBL13758180 | 0.76 | HDAC1 (0.63) | HDAC1HDAC2FABP5HDAC3FABP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492582-B2 | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-8492582-B2 | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-8492582-B2 | N-acyl anthranilic acid derivative or salt thereof | TOYAMA CHEMICAL CO., LTD. (JP) | 2013-07-23 | — | — | US | disclosed |
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2011-11-10 | — | — | US | disclosed |
| EP-2385036-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | Toyama Chemical Co., Ltd. (JP) | 2011-11-09 | — | — | EP | disclosed |
| WO-2010087430-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | 富山化学工業株式会社 (JP) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275797-A1 | N-ACYL ANTHRANILIC ACID DERIVATIVE OR SALT THEREOF | COL14A1, COL2A1, COL1A1 | CYP11B2 833/4885CYP11B1 739/4885HDAC1 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.