Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22609357 | 0.76 | KDM4E (0.36) | SNCAMAPK1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22609348 | 0.69 | PRKAG1 (0.45) | SNCAPTGDR2CYP2C9CYP2C19 | |
| SCHEMBL23453736 | 0.69 | POLB (0.44) | CTSSCTSKSNCAALDH1A1 | |
| SCHEMBL23486291 | 0.66 | LMNA (0.44) | ALDH1A1 | |
| SCHEMBL29027310 | 0.64 | KDM4E (0.39) | ALDH1A1 | |
| SCHEMBL21111928 | 0.60 | MEN1 (0.35) | CTSSCTSKALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL28757628 | 0.59 | TSHR (0.41) | ALDH1A1 | |
| SCHEMBL28005333 | 0.58 | DHODH (0.32) | CTSSCTSK | |
| SCHEMBL27174072 | 0.58 | HAO1 (0.33) | — | |
| SCHEMBL22609313 | 0.58 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3731840-A1 | GLYCOLATE OXIDASE INHIBITORS AND USE THEREOF | Orfan Biotech Inc. (US) | 2020-11-04 | — | — | EP | disclosed |