Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | ARG2 | P78540 | 1/20 | 0.34 |
| ▸ | GGT1 | P19440 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882712 | 0.84 | MEN1 (0.46) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL7253604 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL7320060 | 0.77 | MEN1 (0.41) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL18036525 | 0.77 | MEN1 (0.41) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL16568741 | 0.75 | MEN1 (0.40) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL22612009 | 0.74 | SMPD1 (0.44) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL28099391 | 0.74 | MEN1 (0.43) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL27553149 | 0.73 | MEN1 (0.39) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL4361740 | 0.73 | MEN1 (0.39) | ALDH1A1MEN1CYP1A2KMT2ATHRB | |
| SCHEMBL27413713 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MEN1CYP1A2KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | UBE INDUSTRIES, LTD. (JP) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347011-A1 | DOUBLE-HEADED PROTEASE INHIBITOR | TMPRSS15, SPINT2, PRSS2 | ALDH1A1 1685/4885MEN1 519/4885CYP1A2 1488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.