Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 20/20 | 0.88 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261477 | 0.94 | HTR4 (1.00) | HTR4 | |
| SCHEMBL12227452 | 0.94 | HTR4 (1.00) | HTR4 | |
| SCHEMBL8039331 | 0.94 | HTR4 (1.00) | HTR4 | |
| SCHEMBL8714839 | 0.85 | HTR4 (0.82) | HTR4 | |
| SCHEMBL8714841 | 0.85 | HTR4 (0.82) | HTR4 | |
| SCHEMBL2538722 | 0.82 | HTR4 (0.74) | HTR4 | |
| SCHEMBL16504004 | 0.80 | HTR4 (0.81) | HTR4 | |
| SCHEMBL7429870 | 0.79 | HTR4 (1.00) | HTR4 | |
| Hydrochloric Acid SCHEMBL3170515 | 0.78 | HTR4 (0.98) | HTR4 | |
| SCHEMBL7431308 | 0.77 | HTR4 (0.76) | HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003664-B2 | Indazole-carboxamide compounds | THERAVANCE, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| US-7786136-B2 | Indazole-carboxamide compounds | THERAVANCE, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20080132491-A1 | Indazole-carboxamide compounds | THERAVANCE BIOPHARMA R&D IP, LLC | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132491-A1 | Indazole-carboxamide compounds | HTR4, HTR5A, HTR3B | HTR4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.