Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28887306 | 0.98 | CYP1A2 (0.47) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL28887305 | 0.98 | CYP1A2 (0.47) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL12477330 | 0.84 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL12477334 | 0.84 | CYP1A2 (0.50) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL689292 | 0.82 | THRB (0.46) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL2262266 | 0.82 | CA1 (0.40) | TSHRNFKB1THRB | |
| SCHEMBL31588317 | 0.81 | TSHR (0.41) | GRIK1GRIA4GRIK2GRIK3GRM1 | |
| SCHEMBL23200441 | 0.80 | CYP1A2 (0.54) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL8838342 | 0.80 | CYP1A2 (0.54) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| SCHEMBL496858 | 0.80 | GRM8 (0.62) | CYP1A2GRM8GRM6GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130190409-A1 | DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2013-07-25 | — | — | US | disclosed |
| US-8420121-B2 | Drug delivery vehicles, methods of manufacture, and methods of use thereof | UNIVERSITY OF MASSACHUSETTS (US) | 2013-04-16 | — | — | US | disclosed |
| US-20110200675-A1 | DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF | UNIVERSITY OF MASSACHUSETTS (US) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110200675-A1 | DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF | OGFR, OPRL1, OPRK1 | CYP1A2 820/4885GRM8 1823/4885GRM6 2038/4885 |
| US-20130190409-A1 | DRUG DELIVERY VEHICLES, METHODS OF MANUFACTURE, AND METHODS OF USE THEREOF | OGFR, OPRL1, OPRK1 | CYP1A2 820/4885GRM8 1823/4885GRM6 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.