Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19156089 | 0.88 | KDM4E (0.32) | KDM4E | |
| SCHEMBL22623987 | 0.84 | KDM4E (0.41) | CHRM2CHRM1CHRM3KDM4E | |
| SCHEMBL18716239 | 0.84 | APLNR (0.31) | — | |
| SCHEMBL26327723 | 0.78 | ALDH1A1 (0.32) | KDM4E | |
| SCHEMBL22541975 | 0.78 | — | — | |
| SCHEMBL25859530 | 0.76 | — | — | |
| SCHEMBL20402853 | 0.76 | CHRM2 (0.32) | CHRM2CHRM1CHRM3KDM4E | |
| SCHEMBL23765253 | 0.74 | ALDH1A1 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL11932071 | 0.74 | ALDH1A1 (0.33) | CHRM2CHRM1CHRM3 | |
| SCHEMBL23765298 | 0.74 | ALDH1A1 (0.33) | CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | RIPK1, RIPK2, RIPK4 | CHRM2 3905/4885CHRM1 3837/4885CHRM3 4421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.