Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10202971 | 0.90 | CYP1A2 (0.50) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL7784617 | 0.82 | MAOB (0.53) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL16472055 | 0.82 | PPARA (0.54) | DRD2DRD4DRD3TDP1L3MBTL1 | |
| SCHEMBL15617688 | 0.82 | DRD2 (0.55) | DRD2DRD4DRD3L3MBTL1ALDH1A1 | |
| SCHEMBL10338308 | 0.80 | MEN1 (0.60) | DRD2DRD4DRD3CYP1A2CYP2D6 | |
| SCHEMBL23574899 | 0.80 | LTA4H (0.58) | DRD2DRD4DRD3SMN1; SMN2PPARA | |
| SCHEMBL15959433 | 0.80 | PPARA (0.42) | L3MBTL1SMN1; SMN2PPARA | |
| SCHEMBL13526994 | 0.80 | TDP1 (0.53) | TDP1L3MBTL1ALDH1A1HPGDKDM4E | |
| SCHEMBL13141262 | 0.80 | HRH3 (0.54) | ALDH1A1KDM4ESMN1; SMN2MEN1LMNA | |
| SCHEMBL13526893 | 0.80 | APP (0.47) | SMN1; SMN2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210309633-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-07 | — | — | US | disclosed |
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210309633-A1 | INDAZOLE CARBOXAMIDES AS KINASE INHIBITORS | RIPK3, RIPK1, RIPK2 | DRD2 3785/4885DRD4 4308/4885DRD3 2882/4885 |
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | RIPK1, RIPK2, RIPK4 | DRD2 3796/4885DRD4 4534/4885DRD3 4122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.