Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727214 | 0.80 | HRH1 (0.39) | ACHEKMT2ACXCR4ALDH1A1SMN1; SMN2 | |
| SCHEMBL12384396 | 0.80 | ACHE (0.57) | ACHEALDH1A1CYP3A4SIGMAR1 | |
| SCHEMBL14093043 | 0.80 | ACHE (0.57) | ACHEALDH1A1CYP3A4SIGMAR1 | |
| SCHEMBL15084359 | 0.80 | ACHE (0.81) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| SCHEMBL5824435 | 0.78 | ACHE (0.64) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| SCHEMBL17968039 | 0.78 | ACHE (0.64) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| SCHEMBL14344767 | 0.78 | ACHE (0.64) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4227174 | 0.77 | ACHE (0.62) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| SCHEMBL12013922 | 0.76 | ACHE (1.00) | ACHEKMT2ACYP2A13CXCR4ALDH1A1 | |
| SCHEMBL12727225 | 0.74 | PDCD1 (0.39) | ACHEALDH1A1GAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347071-A1 | AMINOPYRROLOTRIAZINES AS KINASE INHIBITORS | RIPK1, RIPK2, RIPK4 | ACHE 4786/4885KMT2A 3048/4885CYP2A13 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.