Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 2/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22624694 | 0.88 | APP (0.54) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL11507416 | 0.86 | APP (0.57) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL22624757 | 0.84 | LMNA (0.57) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL34475043 | 0.84 | RORC (0.52) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL22624736 | 0.84 | MAPT (0.57) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL34474578 | 0.83 | MEN1 (0.47) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL19327734 | 0.83 | MAPT (0.59) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL22624754 | 0.82 | MYC (0.53) | MEN1KMT2AMAPTPLA2G1BATG4B | |
| SCHEMBL22624762 | 0.82 | KMT2A (0.60) | MEN1KMT2AMAPTGAARAB9A | |
| SCHEMBL22624791 | 0.81 | APP (0.48) | MEN1KMT2AMAPTPLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317076-A9 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2021-10-14 | — | — | US | disclosed |
| US-20200347010-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | UNIV HONG KONG POLYTECHNIC (CN) | 2020-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200347010-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | CFTR, FPR3, FPR1 | MEN1 376/4885KMT2A 4213/4885MAPT 4046/4885 |
| US-20210317076-A9 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | CFTR, FPR3, FPR1 | MEN1 376/4885KMT2A 4213/4885MAPT 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.