Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625406 | 0.90 | TP53 (0.46) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22630038 | 0.89 | RAB9A (0.41) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL25848175 | 0.89 | NPC1 (0.60) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22625066 | 0.89 | RAB9A (0.43) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22624925 | 0.88 | NPC1 (0.55) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22624910 | 0.88 | NPC1 (0.59) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22624996 | 0.87 | NPC1 (0.56) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL25848234 | 0.86 | NPC1 (0.57) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22625229 | 0.86 | NPC1 (0.63) | NPC1RAB9AKDM4EGLAHPGD | |
| SCHEMBL22624981 | 0.85 | NPC1 (0.53) | NPC1RAB9AKDM4EGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | Johnson & Johnson Surgical Vision, Inc. (US) | 2023-07-18 | — | — | US | disclosed |
| EP-3583102-B1 | HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702396-B2 | Hydrophobic compounds for optically active devices | UACA, CRYZ, TRPA1 | NPC1 1051/4885RAB9A 1916/4885KDM4E 4579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.