Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29538955 | 0.77 | CCNA2 (0.43) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL17385442 | 0.77 | CCNA2 (0.49) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL17381607 | 0.77 | CCNA2 (0.43) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL30885867 | 0.77 | CCNA2 (0.43) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL16377789 | 0.76 | TP53 (0.40) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL16377773 | 0.76 | CCNA2 (0.43) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL16377845 | 0.76 | CCNA2 (0.38) | ALDH1A1TP53POLBLMNATSHR | |
| SCHEMBL17385323 | 0.75 | ALDH1A1 (0.51) | ALDH1A1TP53POLBLMNAGAA | |
| SCHEMBL17385521 | 0.67 | L3MBTL1 (0.42) | ALDH1A1TP53POLBL3MBTL1CCNA2 | |
| SCHEMBL3518349 | 0.67 | TP53 (0.40) | ALDH1A1TP53POLBMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013832-B1 | PYRAZOLE COMPOUNDS AS MODULATORS OF FSHR AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |