Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3910099 | 0.86 | MAOB (0.53) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL7381558 | 0.85 | CTSV (0.52) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL27960495 | 0.84 | ALDH1A1 (0.50) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL30158816 | 0.83 | CYP2C9 (0.46) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL28950632 | 0.83 | CYP2C9 (0.46) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL4568026 | 0.83 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2TDP1MAPT | |
| SCHEMBL19123715 | 0.81 | PDK1 (0.52) | NPC1RAB9ASMN1; SMN2CTDSP1TDP1 | |
| SCHEMBL4485886 | 0.81 | PLAU (0.52) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL629633 | 0.81 | ALOX5 (0.47) | NPC1RAB9AHDAC1SMN1; SMN2LTA4H | |
| SCHEMBL30629681 | 0.81 | MAOB (0.43) | NPC1RAB9ASMN1; SMN2TDP1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020223306-A1 | PIM KINASE INHIBITOR COMPOSITIONS AND USES THEREOF | SNAP BIO, INC. (US) | 2020-11-05 | — | — | WO | disclosed |