Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.32 |
| ▸ | LPL | P06858 | 2/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721749 | 0.83 | F11 (0.38) | F11LIPGMEN1KMT2AF2 | |
| SCHEMBL5762336 | 0.82 | JAK2 (0.37) | UCHL1F11LIPGMEN1KMT2A | |
| SCHEMBL28736211 | 0.81 | LIPG (0.36) | F11LIPGMEN1KMT2AF2 | |
| SCHEMBL28811745 | 0.81 | UCHL1 (0.34) | UCHL1F11 | |
| SCHEMBL29020404 | 0.80 | NFE2L2 (0.35) | UCHL1F11MEN1KMT2AF2 | |
| SCHEMBL29175542 | 0.78 | F2 (0.38) | F11LIPGMEN1KMT2AF2 | |
| SCHEMBL6733099 | 0.75 | LIPG (0.37) | UCHL1F11LIPGF2PRSS1 | |
| SCHEMBL2411212 | 0.75 | F2RL3 (0.39) | UCHL1 | |
| SCHEMBL13970721 | 0.75 | KDM4E (0.40) | UCHL1KMT2AHIF1A | |
| SCHEMBL2414737 | 0.74 | LIPG (0.37) | UCHL1F11LIPGLPLCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011084402-A1 | TYROSINE KINASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-07-14 | — | — | WO | disclosed |