Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22633969 | 0.76 | MEN1 (0.55) | LMNAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL5416914 | 0.73 | HIF1A (0.52) | HIF1AADRA1AADRA1DADRA1BALDH1A1 | |
| SCHEMBL29020502 | 0.73 | MEN1 (0.51) | ALDH1A1KDM4EMAPTRAB9ANPSR1 | |
| SCHEMBL22634089 | 0.72 | ALDH1A1 (0.48) | LMNAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22634075 | 0.72 | MAPT (0.50) | LMNAALDH1A1MAPTRAB9ATDP1 | |
| SCHEMBL22638009 | 0.69 | GAA (0.50) | LMNAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22638051 | 0.69 | ALDH1A1 (0.43) | LMNAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22634079 | 0.68 | ALDH1A1 (0.42) | LMNAALDH1A1KDM4EMAPTRAB9A | |
| SCHEMBL22634055 | 0.68 | HIF1A (0.52) | HIF1AADRA1AADRA1DADRA1B | |
| SCHEMBL22633972 | 0.67 | MEN1 (0.56) | LMNAALDH1A1KDM4EMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354318-A1 | THIOSEMICARBAZATES AND USES THEREOF | TST, ABAT, AADAC | HIF1A 3977/4885ADRA1A 3848/4885ADRA1D 3863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.