Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489685 | 0.88 | HTR2C (0.33) | DPP7LMNATDP1CYP3A4TSHR | |
| SCHEMBL28451893 | 0.84 | HTR2C (0.51) | CA2CA1DPP7LMNATDP1 | |
| SCHEMBL27541779 | 0.84 | LMNA (0.47) | CA2CA1LMNATDP1CYP3A4 | |
| SCHEMBL27324758 | 0.84 | NAAA (0.41) | CA2CA1DPP7LMNATDP1 | |
| SCHEMBL27576843 | 0.84 | FAAH (0.45) | CA2CA1DPP7LMNATDP1 | |
| Phthalic Acid SCHEMBL28436486 | 0.84 | ALDH1A1 (0.50) | CA2LMNATDP1CYP3A4TSHR | |
| SCHEMBL29229775 | 0.84 | CYP1A2 (0.47) | CA2CA1DPP7LMNATDP1 | |
| SCHEMBL27351536 | 0.82 | LMNA (0.46) | CA2CA1LMNATDP1CYP3A4 | |
| SCHEMBL27534774 | 0.82 | LMNA (0.55) | LMNATDP1CYP3A4TSHRATM | |
| SCHEMBL28175189 | 0.82 | FAAH (0.44) | CA2CA1DPP7LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227592-A1 | THIOSEMICARBAZATES AND USES THEREOF | THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) | 2020-11-12 | — | — | WO | disclosed |
| CN-104607163-B | A kind of micro- chiral adjusting cellulose chromatography stationary phase, preparation method and applications | 北京迪马欧泰科技发展中心 | 2018-05-15 | — | — | CN | disclosed |
| CN-104607163-A | Micro-chiral adjusting cellulose chromatography stationary phase, as well as preparation method and application thereof | BEIJING SCIENCE & TECH | 2015-05-13 | — | — | CN | disclosed |
| CN-1321969-C | Process for preparing cis-halochrysanthemic acid | SHANGHAI INST ORGANIC CHEM (CN) | 2007-06-20 | — | — | CN | disclosed |
| CN-1390825-A | Process for preparing cis-halochrysanthemic acid | SHANGHAI INST ORGANIC CHEM (CN) | 2003-01-15 | — | — | CN | disclosed |