Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24445503 | 0.82 | ALDH1A1 (0.38) | POLBRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL21583696 | 0.82 | THRB (0.38) | POLBRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL25445775 | 0.81 | CTDSP1 (0.38) | POLBRAB9ASMN1; SMN2CA1CA2 | |
| SCHEMBL373288 | 0.80 | TSHR (0.40) | POLBRAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL157073 | 0.80 | HTT (0.37) | POLBSMN1; SMN2ALDH1A1MAPTCA1 | |
| SCHEMBL11987081 | 0.79 | MAOB (0.41) | POLBRAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9915735 | 0.79 | MAOB (0.41) | POLBRAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4202389 | 0.78 | TSHR (0.44) | POLBRAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL29577269 | 0.78 | TSHR (0.44) | POLBRAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL15910228 | 0.77 | MMP12 (0.43) | RAB9AMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3575879-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC IMAGE-FORMING APPARATUS | CANON KK (JP) | 2022-05-25 | — | — | EP | disclosed |
| US-10831118-B2 | Electrophotographic photosensitive member and method for producing electrophotographic photosensitive member | CANON KABUSHIKI KAISHA (JP) | 2020-11-10 | — | — | US | disclosed |