SCHEMBL373288

SCHEMBL373288

C=C(C)C(=O)OCc1ccccc1N(C)C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.40
ALDH1A1 P00352 5/20 0.40
MAPT P10636 4/20 0.40
GAA P10253 2/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
APP P05067 2/20 0.36
BRD4 O60885 1/20 0.36
ELANE P08246 1/20 0.36
POLB P06746 2/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
AR P10275 1/20 0.34
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
PKM P14618 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10877682 0.85 THRB (0.42) TSHRALDH1A1MAPTGAATP53
SCHEMBL4202389 0.85 TSHR (0.44) TSHRALDH1A1MAPTELANEPOLB
SCHEMBL29577269 0.85 TSHR (0.44) TSHRALDH1A1MAPTELANEPOLB
SCHEMBL22639362 0.80 POLB (0.36) TSHRALDH1A1MAPTGAATP53
SCHEMBL31707533 0.80 ALDH1A1 (0.52) TSHRALDH1A1MAPTSMN1; SMN2ELANE
SCHEMBL1372181 0.80 THRB (0.42) TSHRALDH1A1MAPTELANEPOLB
SCHEMBL10657916 0.79 ALDH1A1 (0.50) TSHRALDH1A1MAPTGAATP53
SCHEMBL9555133 0.79 TSHR (0.39) TSHRALDH1A1MAPTELANEPOLB
SCHEMBL962436 0.79 IDO1 (0.47) TSHRALDH1A1ELANEPOLBAPEX1
SCHEMBL995952 0.79 CYP4F2 (0.45) TSHRALDH1A1MAPTELANEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6576255-B1 Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups ROEHM GMBH & CO. KG (DE) 2003-06-10 US claimed
US-20250215144-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2025-07-03 US disclosed
US-12139574-B2 Polymeric adhesive for anchoring compliant materials to another surface HYALEX ORTHOPAEDICS, INC. (US) 2024-11-12 US disclosed
US-20240076438-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2024-03-07 US disclosed
US-11760830-B2 Polymeric adhesive for anchoring compliant materials to another surface HYALEX ORTHOPAEDICS, INC. (US) 2023-09-19 US disclosed
US-20220287345-A1 SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES EVONIK OPERATIONS GMBH (DE) 2022-09-15 US disclosed
EP-2568967-B2 PHARMACEUTICAL COMPOSITIONS COMPRISING HYDROMORPHONE AND NALOXONE EURO CELTIQUE SA (LU) 2022-07-27 EP disclosed
EP-4009961-A1 SOLUBILITY ENHANCEMENT OF POORLY SOLUBLE ACTIVES Evonik Operations GmbH (DE) 2022-06-15 EP disclosed
US-20210332179-A1 POLYMERIC ADHESIVE FOR ANCHORING COMPLIANT MATERIALS TO ANOTHER SURFACE CUSTOMERS BANK 2021-10-28 US disclosed
CN-112898507-A Silicon block polymer surfactant and preparation method thereof 广东灵捷制造化工有限公司 2021-06-04 CN disclosed
US-20050142174-A1 Adhesive and binding agent for dermal or transdermal treatment systems ROEHM GMBH & CO. KG 2005-06-30 US disclosed
US-20050019381-A1 Binding agent which is stable in storage and used for pharmaceutical applications ROEHM GMBH & CO. KG (DE) 2005-01-27 US disclosed
US-6846891-B2 Coating and binding agent for oral or dermal pharmaceutical forms ROEHM GMBH & CO. KG (DE) 2005-01-25 US disclosed
US-20040249035-A1 Granulate or powder for producing coating or binding agents for medicaments PETEREIT HANS-ULRICH (DE) 2004-12-09 US disclosed
US-20040247687-A1 Method for production of active ingredient-containing pellets ROEHM GMBH & CO. KG (DE) 2004-12-09 US disclosed
US-20030220413-A1 Coating and binding agent for oral or dermal pharmaceutical forms ROEHM GMBH & CO. KG (DE) 2003-11-27 US disclosed
US-6624210-B1 (Meth)acrylate ester copolymer with (meth)acrylate containing tertiary amine group, plasticizer, and emulsifier; powders, pastes, aqueous suspension; encapsulation; drug delivery ROEHM GMBH & CO. KG (DE) 2003-09-23 US disclosed
US-6576255-B1 Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups ROEHM GMBH & CO. KG (DE) 2003-06-10 US disclosed
US-20030064036-A1 Coating and binding agent for pharmaceutical formulations with improved storage stability ROEHM GMBH (DE) 2003-04-03 US disclosed
US-4705695-A AMMONIUM SALT OF TERTIARY AMINE SUBSTITUTED ACRYLIC POLYMER ROHM GMBH CHEMISCHE FABRIK (DE) 1987-11-10 US disclosed