SCHEMBL2263958

SCHEMBL2263958

O=S(=O)(Cl)c1ccc(Cc2ccc(S(=O)(=O)Cl)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TDP1 Q9NUW8 2/20 0.52
HSD17B10 Q99714 1/20 0.52
CA2 P00918 9/20 0.45
CA1 P00915 8/20 0.45
CA9 Q16790 7/20 0.45
CA12 O43570 6/20 0.45
CA14 Q9ULX7 6/20 0.45
HTT P42858 5/20 0.43
SMN1; SMN2 Q16637 5/20 0.42
USP2 O75604 1/20 0.42
HPGD P15428 3/20 0.41
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
STS P08842 1/20 0.41
CYP3A4 P08684 3/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14834008 1.00 ALDH1A1 (0.52) ALDH1A1TDP1HSD17B10CA2CA1
SCHEMBL7244106 0.91 ALDH1A1 (0.62) ALDH1A1TDP1HSD17B10CA2CA1
SCHEMBL11582128 0.84 ALDH1A1 (0.52) ALDH1A1TDP1HSD17B10CA2CA1
SCHEMBL4689723 0.84 CA1 (0.63) ALDH1A1CA2CA1CA9CA12
SCHEMBL651902 0.83 ALDH1A1 (0.71) ALDH1A1TDP1HSD17B10CA2CA1
SCHEMBL396619 0.82 ALDH1A1 (0.50) ALDH1A1TDP1HSD17B10CA2CA1
Methylene Chloride SCHEMBL4686844 0.81 CA1 (0.59) ALDH1A1CA2CA1CA9CA12
SCHEMBL344067 0.80 CA2 (0.61) ALDH1A1TDP1HSD17B10CA2HTT
SCHEMBL297518 0.80 ALDH1A1 (0.48) ALDH1A1TDP1HSD17B10CA2CA1
SCHEMBL4776764 0.80 ALDH1A1 (0.48) ALDH1A1TDP1HSD17B10CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7098296-B2 Preparation of polymeric aryl sulfonamide SUN CHEMICAL CORPORATION (US) 2006-08-29 US claimed
US-20250302760-A1 BIODEGRADABLE, CONTROLLED RELEASE MICROCAPSULES ENCAPSYS, LLC (US) 2025-10-02 US disclosed
EP-3330097-B1 LITHOGRAPHIC PRINTING ORIGINAL PLATE AND PLATE MAKING METHOD FUJIFILM CORP (JP) 2019-10-16 EP disclosed
EP-3330097-A1 LITHOGRAPHIC PRINTING ORIGINAL PLATE AND PLATE MAKING METHOD Fujifilm Corporation (JP) 2018-06-06 EP disclosed
US-20180057509-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2018-03-01 US disclosed
US-20170088559-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2017-03-30 US disclosed
US-9546184-B2 Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines 3M INNOVATIVE PROPERTIES COMPANY (US) 2017-01-17 US disclosed
US-20150266901-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES 3M INNOVATIVE PROPERTIES CO (US) 2015-09-24 US disclosed
US-9120726-B2 Radiation-sensitive resin composition, compound and producing method of compound JSR CORPORATION (JP) 2015-09-01 US disclosed
US-9120726-B2 Radiation-sensitive resin composition, compound and producing method of compound JSR CORPORATION (JP) 2015-09-01 US disclosed
US-5208316-A CYCLODEXTRIN POLYMER AND CYCLODEXTRIN MEMBRANE PREPARED USING SAID POLYMER TOPPAN PRINTING CO., LTD. (JP) 1993-05-04 US disclosed
EP-0178183-B1 PREPARATION OF AROMATIC KETONE-SULFONE COPOLYMERS RAYCHEM CORPORATION (a Delaware corporation) (US) 1993-01-20 EP disclosed
EP-0502194-A1 CYCLODEXTRIN POLYMER AND CYCLODEXTRIN FILM FORMED THEREFROM Toppan Printing Co., Ltd. (JP) 1992-09-09 EP disclosed
EP-0485614-A1 CYCLODEXTRIN DERIVATIVE Toppan Printing Co., Ltd. (JP) 1992-05-20 EP disclosed
WO-1991005605-A1 CYCLODEXTRIN LABELS FOR IMMUNOASSAY AND BIOCHEMICAL ANALYSIS KOSAK KENNETH M (US) 1991-05-02 WO disclosed
EP-0128700-B1 IMPROVEMENTS IN MICROCAPSULES MOORE BUSINESS FORMS, INC. (US) 1987-07-22 EP disclosed
US-4599271-A FORMING POLYMERIC WALLS AROUND ORGANIC DROPLETS MOORE BUSINESS FORMS, INC. (US) 1986-07-08 US disclosed
US-4593086-A From carboxylic acid halide and aromatic dicarboxylic acid dihalide RAYCHEM CORPORATION (US) 1986-06-03 US disclosed
EP-0178183-A2 Preparation of aromatic ketone-sulfone copolymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
US-4495509-A CONTINUOUS POLYMERIC WALL SURROUNDING A COLORLESS DYE PRECURSOR MOORE BUSINESS FORMS, INC. (US) 1985-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266901-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885TDP1 3278/4885HSD17B10 1809/4885
US-20170088559-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885TDP1 3278/4885HSD17B10 1809/4885
US-20180057509-A1 ALKYLOXY SUBSTITUTED THIAZOLOQUINOLINES AND THIAZOLONAPHTHYRIDINES IL2, IFNG, TSLP ALDH1A1 624/4885TDP1 3278/4885HSD17B10 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.