Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | CTSZ | Q9UBR2 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 9/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949790 | 0.77 | CA12 (0.48) | ALDH1A1KDM4EMAPT | |
| SCHEMBL23949896 | 0.77 | MEN1 (0.63) | ALDH1A1KDM4ETSHRMAPTPKM | |
| SCHEMBL10986702 | 0.74 | ALDH1A1 (0.57) | ALDH1A1KDM4ERAB9ATSHRHSD17B10 | |
| SCHEMBL14408085 | 0.74 | ALDH1A1 (0.61) | ALDH1A1CTSZKDM4ERAB9ATSHR | |
| Bromide SCHEMBL10981546 | 0.73 | ALDH1A1 (0.56) | ALDH1A1KDM4ERAB9ATSHRHSD17B10 | |
| SCHEMBL5375177 | 0.73 | HSD11B1 (0.57) | ALDH1A1CTSZKDM4ERAB9ATSHR | |
| Bromide SCHEMBL11197730 | 0.72 | ALDH1A1 (0.55) | ALDH1A1KDM4ERAB9ATSHRHSD17B10 | |
| SCHEMBL14408074 | 0.72 | ALDH1A1 (0.59) | ALDH1A1CTSZKDM4ERAB9ATSHR | |
| SCHEMBL653025 | 0.70 | PKM (0.87) | ALDH1A1TSHRPKM | |
| SCHEMBL23949801 | 0.70 | GAA (0.57) | ALDH1A1RAB9AHSD17B10MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10828281-B2 | Non-hydrophobic compounds for use in treating metastasis and/or cartilage defect | VIM, MATR3, TP53 | ALDH1A1 1636/4885CTSZ 262/4885KDM4E 4343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.