Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 10/20 | 0.42 |
| ▸ | MGAM | O43451 | 9/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.42 |
| ▸ | SI | P14410 | 9/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 9/20 | 0.42 |
| ▸ | F12 | P00748 | 5/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23591735 | 0.80 | DGAT1 (0.46) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL25494140 | 0.80 | MAPT (0.44) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL20458633 | 0.77 | HTT (0.31) | HTT | |
| SCHEMBL21203205 | 0.74 | DGAT1 (0.51) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL20108539 | 0.73 | DGAT1 (0.47) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL2490623 | 0.72 | MAPT (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL3462909 | 0.72 | MAPT (0.61) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL20850940 | 0.70 | DGAT1 (0.50) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL3689328 | 0.68 | GAA (0.58) | DGAT1GAAMGAMAMY1ASI | |
| SCHEMBL459733 | 0.68 | GAA (0.60) | DGAT1GAAMGAMAMY1ASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116858-B1 | AZASPIRO DERIVATIVES AS TRPM8 ANTAGONISTS | RAQUALIA PHARMA INC (JP) | 2020-11-11 | — | — | EP | disclosed |