Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22579255 | 0.96 | MAPT (0.42) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22579295 | 0.94 | HDAC1 (0.42) | MAPTFGFR1RAB9ASMN1; SMN2LTB4R | |
| SCHEMBL22579236 | 0.90 | ABCB1 (0.41) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL22641675 | 0.89 | MAPT (0.47) | MAPTFGFR1RAB9AMEN1KMT2A | |
| SCHEMBL22579300 | 0.85 | ADH5 (0.48) | MAPTMEN1KMT2ASMN1; SMN2LTB4R | |
| SCHEMBL22641730 | 0.83 | MAPT (0.48) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22641632 | 0.83 | HDAC3 (0.50) | MAPTPTGS2KDM4ELMNAHDAC3 | |
| SCHEMBL22579221 | 0.80 | PTGS2 (0.53) | MAPTFGFR1RAB9AMEN1KMT2A | |
| SCHEMBL22579202 | 0.77 | FGFR1 (0.50) | MAPTFGFR1RAB9AMEN1KMT2A | |
| SCHEMBL22579263 | 0.76 | MAPT (0.53) | MAPTRAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3736266-A1 | COMPOUND SIMULTANEOUSLY INHIBITING LSD1 AND HDAC TARGETS AND APPLICATION THEREOF | Peking University Shenzhen Graduate School (CN) | 2020-11-11 | — | — | EP | disclosed |