Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDC14B | O60729 | 1/20 | 0.43 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.43 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28222522 | 0.89 | MAOA (0.57) | MAPTNPC1KMT2AALDH1A1GLA | |
| SCHEMBL7067143 | 0.85 | ALDH1A1 (0.54) | MAPTNPC1KMT2AALDH1A1GLA | |
| SCHEMBL29685650 | 0.84 | ALDH1A1 (0.54) | MAPTALDH1A1GLATSHRGAA | |
| SCHEMBL516363 | 0.84 | ALDH1A1 (0.54) | MAPTALDH1A1GLATSHRGAA | |
| SCHEMBL23098845 | 0.82 | TTR (0.48) | MAPTNPC1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL22645256 | 0.81 | MAPT (0.51) | MAPTNPC1KMT2AALDH1A1AKR1C3 | |
| SCHEMBL8602215 | 0.81 | MAOA (0.51) | MAPTNPC1KMT2AALDH1A1GLA | |
| SCHEMBL4586087 | 0.79 | ALDH1A1 (0.53) | MAPTNPC1ALDH1A1GLAGAA | |
| SCHEMBL30476189 | 0.79 | ALDH1A1 (0.76) | MAPTNPC1KMT2AALDH1A1GLA | |
| SCHEMBL2012858 | 0.79 | ALDH1A1 (0.76) | MAPTNPC1KMT2AALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10836723-B2 | Method for synthesizing sodium 2,2,6,6-tetramethylpiperidides | KOBELCO ECO-SOLUTIONS CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |